Our school is preschool-6th, with about 185 kids, maybe 140 families. So we are about twice as big as yours. Because it is heavily weighted to preschool through K, we can't really have any sales that target kid prizes, etc, plus our admin is philosophically opposed to that. We also can't do Santa/Christmas thing because we are very multiethnic/international.
We do a wrapping paper (Innisbrook) that made $4000 last year. We do the Scholastic book fair, which does great, with either a couple thousand in cash profits (or more if we take Scholastic credit).
We do Box Tops and Cartridge Recycling, both of which don't cost anyone anything, and which make a couple hundred dollars each year.
We also sell little things at a School Spirit Store a few times a year. It is all stuff from Oriental Trading Company (cute pencils, erasers, novelty notebooks, pencil grips, etc.). They are all cheap, and we can mark them up. For example, you can get these cute neon erasers that look like flip-flop sandals - 144 erasers for $3.95. So they cost you 3 cents each, you can sell them for 5. There are little notepads with cute covers that are 24 for $4.95. You get the idea.
We also sell school t-shirts and sweatshirts, which are not expensive if you shop around and you can get tote bags, etc. as well for parents or grandparents. We have samples and then do one big order in the fall.
Our big fundraiser is an auction of art items made by the classes, combined with either additional auction stuff, a Monte Carlo night, or a carnival. But I don't know that any really big fundraiser makes sense for a school your size.